RADIOIMMUNOLOGICAL DETERMINATION OF SERUM 3 BETA-HYDROXY-5-CHOLENOIC ACID IN NORMAL SUBJECTS AND PATIENTS WITH LIVER DISEASE.

Radioimmunological determination of serum 3 beta-hydroxy-5-cholenoic acid in normal subjects and patients with liver disease.

A radioimmunoassay for the determination of 3 beta-hydroxy-5-cholenoic acid in human serum has been developed, using 3 beta-hydroxy-5-cholenoyl-thyroglobulin as immunogen and 3 beta-hydroxy-5-cholenoylglycyl-125I histamine as radioactive ligand.The association constant was 6.3 X 10(8) l/mol.Cross reactivity with other bile acids of human serum was

read more


BrdU Pulse Labelling In Vivo to Characterise Cell Proliferation during Regeneration and Repair following Injury to the Airway Wall in Sheep

The response of S-phase cells labelled with bromodeoxyuridine (BrdU) in sheep airways undergoing repair in response to endobronchial brush biopsy was investigated in this study.Separate sites within the airway tree of anaesthetised sheep Rugby Jacket were biopsied at intervals prior to pulse labelling with BrdU, which was administered one hour prio

read more

Improving sea surface temperature in a regional ocean model through refined sea surface temperature assimilation

Infrared (IR) and passive microwave (PMW) satellite sea surface temperature (SST) retrievals are valuable to assimilate into high-resolution regional ocean forecast models.Still, there are issues related to these SSTs that need to be addressed to achieve improved ocean forecasts.Firstly, satellite SST products tend to be biased.Assimilating SSTs fr

read more